منابع مشابه
An evaluation of false-positive rifampicin resistance on the Xpert MTB/RIF
BACKGROUND Mycobacterium tuberculosis (MTB) is one of the most significant causes of mortality and morbidity. Early diagnose is important especially in multiple drug resistant tuberculosis to avoid transmission. Traditional techniques requires at least one to three weeks for diagnosis of tuberculosis. Diagnostic delays with multiple drug resistant tuberculosis are associated with worse clinical...
متن کاملFalse-positive rifampicin resistance on Xpert® MTB/RIF: case report and clinical implications.
The World Health Organization had endorsed Xpert® MTB/RIF (Xpert) as the initial diagnostic for multidrug-resistant tuberculosis (TB) or TB suspects co-infected with the human immunodeficiency virus. We investigated an unexpected case of rifampicin (RMP) resistance on Xpert using repeat Xpert, smear microscopy, MTBDRplus assay, culture, drug susceptibility testing, spoligotyping and rpoB gene ...
متن کاملHigh positive predictive value of Xpert in a low rifampicin resistance prevalence setting.
Although drug susceptible tuberculosis (TB) is a curable disease, spread of rifampicin-resistant TB, including multidrug-resistant (MDR)and extensively drug-resistant (XDR)-TB, is a threat to disease control worldwide [1], in particular in Eastern Europe [2]. XpertMTB/RIF (Xpert; Cepheid Inc., Sunnyvale, CA, USA) is an accurate [3] and affordable [4] automated PCR-based assay that detects DNA o...
متن کاملFalse-positive Xpert® MTB/RIF assays in previously treated patients: need for caution in interpreting results.
Xpert(®) MTB/RIF is the initial diagnostic test of choice for tuberculosis (TB). It is not known if false-positive results are more common in previously treated patients. We report four patients with successful treatment for TB up to 5 years previously who presented with respiratory tract infection and were Xpert-positive, but had negative TB cultures and clinical improvement without anti-tuber...
متن کاملHIV false positive results and Flu vaccination
Abstract False positive results are the major problem influencing interpretation of Clinical Laboratory test. They are originated mostly in the other diseases, technical errors and the recent vaccination. The problem has been presented since 1991 is positive HIV test after influenza Vaccination (1). The False positive has been reported in Cases using Eliza, one of The most common test to screen...
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ژورنال
عنوان ژورنال: The Lancet Microbe
سال: 2020
ISSN: 2666-5247
DOI: 10.1016/s2666-5247(20)30123-3